All Articles
Injectables5 min readMarch 2026

Cellenis Derma PRP vs. Regular PRP: What's the Difference?

Both use your own platelet-rich plasma — but they serve very different purposes. Here's how to know which one is right for your goals.

S

Sally Mills, DNP, MLS, ACNP-BC, CPNP-AC, CCRN

Founder · 25+ Years Clinical Experience

PRP — platelet-rich plasma — has become one of the most versatile tools in aesthetic medicine. At The Skin Cliniq, we use PRP in two distinct ways: as Cellenis Derma PRP, a natural bio-filler for facial volume and skin quality, and as standard PRP paired with microneedling or hair restoration treatments. Same biology, very different applications.

What PRP Actually Is

PRP is made from your own blood. A small sample is drawn, then spun in a centrifuge to separate and concentrate the platelets — the components responsible for healing and growth factor release. That concentrated plasma is then applied or injected where it's needed.

Because PRP comes entirely from you, there are no synthetic compounds, no foreign materials, and no risk of allergic reaction. It works by releasing growth factors that signal your body's own repair and regeneration pathways.

Cellenis Derma PRP — The Natural Bio-Filler

Cellenis Derma PRP is a specialized PRP application designed to work as a natural alternative to synthetic dermal fillers. The Cellenis system uses a proprietary preparation method to produce a gel-like PRP that can be injected into areas of volume loss — cheeks, temples, under-eyes, and lips — to restore fullness and improve skin quality simultaneously.

What makes it distinct from traditional fillers:

  • Results are entirely your body's own — no hyaluronic acid, no synthetic material
  • Improves overall skin texture and quality alongside volumizing, something HA fillers don't do
  • Results build gradually over 4–6 weeks as your body responds
  • Most clients benefit from more than one session; the exact number is determined during consultation and based on individual results

Standard PRP — For Healing, Stimulation & Restoration

When PRP is used alongside microneedling or as part of hair restoration therapy, the goal is different: stimulation and repair rather than volume. In these applications, the liquid PRP is applied to freshly treated skin or injected into the scalp to amplify the body's healing response — accelerating collagen production, increasing follicle activity, and deepening results.

Standard PRP applied with microneedling significantly boosts the collagen cascade triggered by the needling channels. In hair restoration, PRP injected at follicle depth — and now also combined with the Nouvaderm laser at The Skin Cliniq — promotes transition of weakened follicles back into active growth phase.

Which One Is Right for You?

The answer depends entirely on your goals:

  • Facial volume loss, skin quality, natural filler alternative → Cellenis Derma PRP
  • Skin renewal, scar improvement, collagen stimulation → PRP + Microneedling
  • Hair thinning, scalp health, follicle reactivation → PRP Hair Restoration

Many clients benefit from more than one PRP application across different treatments. Sally will assess your full picture during your consultation and recommend the approach — or combination — most likely to deliver the results you're after.

Ready to Take the Next Step?

Book a Consultation

Sally will assess your skin, answer your questions, and curate a treatment plan built entirely around you.

Find Us

Historic Downtown
Loveland, OH

113 Karl Brown Way

Loveland, OH 45140

Get Directions